Urinary tract infections (UTIs), is an infection caused by pathogenic organisms such as, bacteria, fungi, or parasites, The most common bacterial to cause these infections are uropathogenic Escherichia coli (UPEC), aka E. coli., affecting more than 150 million people worldwide every year .According to research published in March 2012 in the journal Emerging Infectious Diseases,E. coli is responsible for more than 85 percent of all urinary tract infections. These bacteriatypically initiate UTIs by invading the superficial epithelium that lines the bladder lumen, called urothelial cells.There are many risk factors for UTIs. Changes in the sexual activity, pregnancy, and menopausal status have a high influence risk for UTI occurrence since all of them affect the urogenital bacterial composition.

Most UTIs are uncomplicated and don’t cause any lasting harm to the urinary tract. But UTIs that aren’t treated can progress to the kidneys, where permanent damage can occur. Symptoms of such conditions often include pain in the lower back (flank pain on one or both sides), fever, chills, nausea, and/or vomiting. However, it’s usually a minor illness when an infection affects the bladder. Many effective OTC UTI treatment options, such as Nepbio’s (NBI) URICIL for UTI, can help treat your UTIs.

Nepbio (NBI) – Neptune Bio-Innovations is a wholly-owned Australian business. Nepbio (NBI) develops innovative consumer health and wellness products to help Australians live a healthy lifestyle. Nepbio (NBI)'s range of healthy food, nutrition, wellness, and consumer health products helps reduce the risk of diabetes, hypertension, dehydration, and more.

In our last article, we spoke about UTI And Pregnancy. Today, we will talk about E. coli, how they can lead to UTIs, and what makes Nepbio’s (NBI) URICIL the most sought-after medication for UTIs.

[1]Stamm, W. E. &Norrby, S. R. Urinary tract infections: disease panorama and challenges. J. Infect. Dis. 183, S1–S4 (2001).

About UTI

UTI stands for urinary tract infection caused by Escherichia coli (E. coli) bacteria that normally lives in the intestines.It’s also found in the gut of some animals.Most types of E. coli are harmless. It even helps keep the digestive tract healthy. But some strains can cause diarrheaif contaminated food or drink fouled wate was consumed.

E. coli is associated with food poisoning. But pneumonia and urinary tract infections can be from different types of the bacteria. Strains, such as E. coli O157:H7, affect organs within the urinary system in the human body, such as the kidney, bladder, urethra, and ureters, causing severe stomach cramps, bloody diarrhea, vomiting, inflammation and irritation.

E.coli is a normal resident of the bowel,. Since the urethra is close to the anus, this bacteria from the large intestine can sometimes move from the anus and into the urethra, which is how it makes it way to the urinary tract. If the infection isn't treated, it can continue to infect the kidneys. UTIs predominantly affect women since they have shorter urethras than men, making it easier for bacteria to get to their bladders.

UTIs, which can range from bladder infections to kidney infections, are among the most common and debilitating bacterial infections. UTIs in the bladder and urethra can be treated if acted upon immediately. Young children and older adults have a greater risk of developing a life-threatening form of kidney failure.

E. Coli & UTI

Most types of E. coli are harmless. They even help keep our digestive tract healthy. Then, there are some strains that can cause diarrhea if contaminated food is consumed or drinking fouled water.But, there some versions of E. coli that make you sick by making a toxin called Shiga that damages the lining of the intestine. One especially bad strain, O157:H7, can causeabdominal cramps, vomiting, and bloody diarrhea . It is the leading cause of acute kidney failure in children . It can also cause life-threatening symptoms like adult kidney failure, fever, bleeding, confusion and seizures. Seek medical help if you have one of these symptoms


You can be infected even with the small amount of exposuretoE.coli. Potential sources of exposure include contaminated food or water — especially raw fruits and vegetables, undercooked ground beef, and unpasteurised milk.

Signs & symptoms of UTI

Symptoms of a UTI can differ from one person to another. Some individuals may not experience any signs at all. But for most people, this illness is uncomfortable and extremely painful.

Some common symptoms include:

  • Pain and burning urination (dysuria)

  • Needing to pee more often than usual, especially during the night(nocturia)

  • Pee is cloudy, dark, bloody, or has a strong smell

  • Needing to pee suddenly or more urgently than usual

  • Lower abdomen pain or pain in your back, just under the ribs

  • Fever or chills (a sign that the infection may have reached your kidneys)

  • Feeling tired or shaky

A urine dipstick test can reveal the clinical signs of UTI, including blood and pus cells in the urine sample.


URICIL is a Urinary Tract Infection (UTI) over-the-counter medicine for cystitis. URICIL kills the uropathogenic bacteria that cause UTIs and provides relief from scalding pain. Interlaboratory studies have demonstrated the patented hydroxyl curcuminoid is a potent antibacterial and anti-inflammatory substance which kills 99% of uropathogenic bacteria.

URICIL is a 2-in-1 urinary alkalizer and natural antibacterial that can help treat your UTIs effectively. URICIL is a safe and efficacious over-the-counter medicine with a natural potent antibacterial agent that can be used in therapeutic prophylactic and symptomatic relief from UTIs. It is suitable for recurrent UTIs.

Curcumin, the main compound in Nepbio’s (NBI) URICIL, has been hydrolyzed to act as antibiotics, helps to fight infections, and reduces its recurrence significantly. Hydroxyl Curcumin, a natural patented ingredient in URICIL, is a potent antibacterial that eliminates all chances of antibiotic resistance that arises from prolonged antibiotic usage, an anti-inflammatory agent that helps to relieve the inflammation of the bladder during cystitis, and a Potent Antioxidant.

The potassium citrate in URICIL makes it a Urinary Alkaliser- makes the urine less acidic and helps to relieve the painful burning sensation when urinating, a common symptom of UTI.

Taking a Urinary Alkaliser and Natural Antibacterial OTC medication like URICIL helps relieve various UTI symptoms and reduce the occurrence of medically diagnosed cystitis, the most common type of UTI. The patented hydroxyl curcuminoid is a potent antibacterial and anti-inflammatory substance which kills 99% of uropathogenic bacteria. And Curcuminoids are extracted from natural turmeric.

URICIL is a safe and efficacious over-the-counter medicine with a natural potent antibacterial agent that can be used in therapeutic, prophylactic, and symptomatic relief from UTIs. It is suitable for recurrent UTIs.

Eliminate E. coli from your system with our 2 in 1 Natural Anti-bacterial and Urinary Alkaliser, URACIL. It is a popular over-the-counter treatment for UTIs and can be found in all good pharmacies. You can also shop for URICIL online at www.nepbio.com. Try the medication yourself to believe its effectiveness.

About Nepbio (NBI)

Nepbio (NBI) is a global leader in scientific research and development of dietary supplements, medicines, and food products for a healthier lifestyle. We aim to keep chronic diseases such as obesity, hypertension, and diabetes at bay simply by advocating healthy dietary habits using healthy food. We have a wide range of innovative health & wellness products:

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URICIL is a Urinary Tract Infection (UTI) over-the-counter medicine for cystitis. URICIL helps to relieve symptoms and reduce the occurrence of medically diagnosed cystitis. #URICIL, #cystitismedicine, #UTI, #cystitis

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